POTENTIAL "ANTIBIOTICS" FROM FLOWERING PLANTS
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Bioinformatics Infrastructure facility Center of Department of Biotechnology
P.G.& Research Dept. of Microbiology and Biotechnology
Presidency College(Aut.)
CHENNAI-600 005
 
 
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JUSTICIDIN A

 

Justicia procumbens



Haplophyllum tuberculatum




Freshly powder


 

Justicidin A is an arylnaphthalide lignan


Source: Justicia hayatai var.decumbens,Justicia procumbens Linn.var.leucantha Honda,Justicia procumbens Linn. Haplophyllum cappadocicum Spach. Haplophyllum tuberculatum (Forsk.)A.Juss, Rostellularia procumbens.


Physico chemical Properites: A naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum

Studies on In vitro antiviral activity:
Antiviral activity(MTC:>0.25g/ml)against vesicular stomatitis virus and low cytotoxicity(MTC:>31g/ml)against cultured rabbit lung cells (RL-33) potent cytotoxic effects , and enhanced TNF-generation in LPS-stimulated.

Studies on In vivo antiviral activity: Nil

Genomic information: Nil

Structure of Justicidin A

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